Fig. 31. TEM of the central cavity (CC) of a stage 2, 8-cell embryo in vitro, 72 hours post-insemination, (original magnification x2780). Five polyhedral-shpaed blastomeres surround the cavity and have close contact along their radial margins leaving little intercellular space between them. A bleb of cytoplasm and some cellular debris are in the cavity. A collection of unreleased cortical granules is in one blastomere (arrowhead).

B, cytoplasmic bleb; M, mitochondria; N, nucleus; SS, subzonal space; V, vacuole; ZP, zona pellucida.

(From: Sathananthan, Wood, and Leeton, 1982. Reproduced with permission of the publisher, Elsevier.)

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